Andreas Schäfer Selected Research

Chemokine CX3CL1

6/2015	Modulation of platelet and monocyte function by the chemokine fractalkine (CX3 CL1) in cardiovascular disease.
4/2014	Fractalkine promotes platelet activation and vascular dysfunction in congestive heart failure.
9/2012	Fractalkine--a local inflammatory marker aggravating platelet activation at the vulnerable plaque.
1/2012	Fractalkine is expressed in early and advanced atherosclerotic lesions and supports monocyte recruitment via CX3CR1.
8/2007	Chemokine fractalkine mediates leukocyte recruitment to inflammatory endothelial cells in flowing whole blood: a critical role for P-selectin expressed on activated platelets.
1/2007	The CX3C chemokine fractalkine induces vascular dysfunction by generation of superoxide anions.
1/2004	Novel role of the membrane-bound chemokine fractalkine in platelet activation and adhesion.

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Andreas Schäfer Research Topics

Disease

19	Myocardial Infarction 03/2022 - 10/2002
18	Heart Failure 01/2022 - 10/2002
10	Cardiogenic Shock 01/2022 - 01/2017
8	Out-of-Hospital Cardiac Arrest 01/2022 - 01/2018
7	ST Elevation Myocardial Infarction 11/2022 - 10/2012
7	Thrombosis (Thrombus) 06/2021 - 05/2007
6	Atrial Fibrillation 01/2022 - 08/2013
6	Hemorrhage 01/2022 - 09/2016
6	Stroke (Strokes) 01/2022 - 09/2016
5	Infarction (Infarctions) 03/2022 - 09/2014
5	Shock 01/2022 - 01/2018
5	Coronary Artery Disease (Coronary Atherosclerosis) 01/2022 - 01/2007
5	Atherosclerosis 06/2015 - 01/2004
4	Diabetes Mellitus 06/2022 - 09/2004
4	Acute Coronary Syndrome 01/2022 - 01/2020
3	Neoplasms (Cancer) 03/2022 - 10/2017
3	Heart Arrest (Cardiac Arrest) 11/2021 - 08/2002
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 01/2008
3	Parkinson Disease (Parkinson's Disease) 09/2014 - 01/2012
2	Myocarditis (Carditis) 01/2022 - 01/2020
2	Hypoxia (Hypoxemia) 01/2022 - 07/2014
2	Chronic Renal Insufficiency 07/2021 - 01/2017
2	Coronary Stenosis (Coronary Artery Stenosis) 01/2021 - 01/2018
2	Sepsis (Septicemia) 01/2021 - 01/2020
2	Cardiomyopathies (Cardiomyopathy) 03/2020 - 08/2016
2	Pulmonary Edema 01/2019 - 07/2014
2	Pulmonary Embolism 01/2019 - 08/2013
2	Venous Thromboembolism 07/2017 - 01/2015
2	Vascular System Injuries 01/2017 - 01/2004
2	Inflammation (Inflammations) 12/2015 - 11/2006
2	Myocardial Ischemia (Ischemic Heart Diseases) 07/2014 - 06/2008
2	Atherosclerotic Plaque (Atheroma) 01/2012 - 01/2008
2	Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature 08/2011 - 04/2010
1	Chronic Kidney Failure (Chronic Renal Failure) 12/2022
1	Mitral Valve Insufficiency (Mitral Regurgitation) 06/2022
1	Rib Fractures (Rib Fracture) 01/2022
1	Wounds and Injuries (Trauma) 01/2022
1	Ventricular Dysfunction 01/2022
1	Spinal Fractures 01/2022
1	Ventricular Tachycardia 01/2022
1	Critical Illness (Critically Ill) 07/2021
1	Colorectal Neoplasms (Colorectal Cancer) 05/2021

Drug/Important Bio-Agent (IBA)

9	Clopidogrel (Plavix)FDA Link 01/2022 - 02/2007
7	Chemokine CX3CL1IBA 06/2015 - 01/2004
7	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2014 - 01/2004
6	AnticoagulantsIBA 01/2022 - 01/2015
5	ChemokinesIBA 06/2015 - 01/2004
4	Lactic Acid (Lactate)FDA LinkGeneric 06/2022 - 01/2020
4	Prasugrel Hydrochloride FDA Link 01/2022 - 10/2012
3	Vitamin K FDA Link 01/2022 - 07/2017
3	N(4)-oleylcytosine arabinosideIBA 06/2021 - 09/2016
3	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 01/2017 - 06/2003
3	Mineralocorticoid Receptor AntagonistsIBA 01/2017 - 06/2003
3	salicylhydroxamic acid (SHAM)IBA 03/2004 - 10/2002
2	Glucose (Dextrose)FDA LinkGeneric 11/2022 - 09/2014
2	TicagrelorIBA 01/2022 - 01/2022
2	RivaroxabanIBA 01/2022 - 08/2013
2	Phosphopyruvate Hydratase (Enolase)IBA 01/2022 - 01/2021
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2017
2	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA 07/2021 - 01/2020
2	edoxabanIBA 07/2017 - 09/2016
2	von Willebrand FactorIBA 01/2017 - 01/2017
2	Chemokine ReceptorsIBA 12/2015 - 06/2015
2	5- chloro- 2- (5- chlorothiophene- 2- sulfonylamino)- N- (4- (morpholine- 4- sulfonyl)phenyl)benzamideIBA 07/2014 - 11/2010
2	Superoxides (Superoxide)IBA 07/2014 - 10/2002
2	Guanylate Cyclase (Guanylyl Cyclase)IBA 11/2010 - 12/2006
2	Adenosine Diphosphate (ADP)IBA 10/2008 - 06/2008
2	Streptozocin (Streptozotocin)FDA Link 09/2007 - 05/2007
2	Rosuvastatin Calcium (Crestor)FDA Link 05/2007 - 05/2005
2	Eplerenone (Inspra)FDA LinkGeneric 06/2003 - 06/2003
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 06/2003 - 06/2003
2	trandolapril (Mavik)FDA LinkGeneric 06/2003 - 06/2003
1	Fibrinogen (Factor I)FDA Link 06/2022
1	Oxygen (Dioxygen)IBA 03/2022
1	Interleukin-6 (Interleukin 6)IBA 01/2022
1	Antiviral Agents (Antivirals)IBA 01/2022
1	Tenofovir (Viread)FDA Link 01/2022
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	68Ga-FAPIIBA 01/2022
1	1-phenyl-3,3-dimethyltriazene (PDT)IBA 07/2021

Therapy/Procedure

20	Therapeutics 06/2022 - 10/2002
10	Percutaneous Coronary Intervention 01/2022 - 01/2017
8	Extracorporeal Membrane Oxygenation 01/2022 - 01/2017
5	Induced Hypothermia 11/2021 - 01/2016
4	Secondary Prevention 03/2022 - 07/2017
4	Cardiopulmonary Resuscitation (CPR) 01/2022 - 01/2016
4	Ligation 01/2015 - 05/2005
3	Heart-Assist Devices 01/2022 - 01/2019
3	Dual Anti-Platelet Therapy 01/2022 - 01/2020
3	Drug Therapy (Chemotherapy) 01/2022 - 10/2017
3	Stents 06/2021 - 06/2008
2	Catheters 12/2022 - 01/2022
2	Transcatheter Aortic Valve Replacement 01/2022 - 01/2020
2	Critical Care (Surgical Intensive Care) 10/2020 - 08/2002
2	Resuscitation 01/2020 - 01/2018
1	Renal Dialysis (Hemodialysis) 12/2022
1	Ablation Techniques 03/2022
1	Airway Management 07/2021
1	Brachytherapy 05/2021